Metachronous bilateral ovarian metastasis with spontaneous rupture following curative resection of stage T4a colon cancer: a case report and literature review - 华体会
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September 28, 2026
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BackgroundColorectal cancer (CRC) metastasizes to the ovary in approximately 0.8–7.4% of cases, typically indicating aggressive biology and poor prognosis. Metachronous bilateral ovarian involvement with spontaneous rupture is exceptionally rare, and the distinction between signet-ring cell (Krukenb...